The Agoracoma project

Photo by Mariana Montrazi on Pexels

Coma is a state of transient loss of consciousness from which the patient may emerge after a variable period, sometimes passing through an intermediate stage of impaired consciousness. Even today, it remains extremely difficult to assess consciousness (diagnosis) and/or predict its return (prognosis).

Our project aims to gain a better understanding of:

  • how various biological markers (cerebral, cardiac, behavioral, etc.) interact with one another and with the environment—in a naturalistic setting (using emotional or social stimuli, such as the presence of loved ones)—during the recovery of consciousness
  • how the mental representations of consciousness held by those assessing it (healthcare professionals and loved ones) influence diagnosis and prognosis.
To this end, we propose to:

  • create a new local multidisciplinary consortium focused on the recovery of consciousness—encompassing medicine, rehabilitation, neuroscience, psychopathology, cognitive-behavioral psychology, philosophy, anthropology, epistemology, and artificial intelligence—while leveraging an extensive local network of universities, hospitals, family associations, academic programs, and the arts;
  • promote interdisciplinary approaches by integrating concepts and methodologies through multimodal data acquisition (behavior, brain activity, interviews, observations, clinical data, etc.) and multidimensional analysis (data fusion, deep learning, computer vision, cross-analysis of speech and observations, etc.);
  • promote a transdisciplinary epistemological approach by developing a model of consciousness and a new methodology for transdisciplinarity;
  • facilitate the flow of knowledge through a back-and-forth exchange between practice and theory, with the aim of improving care, diagnosis, and prognosis.
Photo by Jr Korpa on Unsplash

Project leaders:

The Agoracoma group consists of nine co-leads interested in the return of consciousness after a coma.

Maude BEAUDOIN

Maude Beaudoin is a neuroscience researcher at the Centre de Recherche en Neurosciences de Lyon (UCBL, CNRS, Inserm).

Stefan DUFFNER

Stefan Duffner is a computer science faculty member and researcher at the Laboratoire d’Informatique en Images et Systèmes d’Information (LIRIS, CNRS, INSA, UCBL, UL2, École Centrale de Lyon).

Florent GOBERT

Florent Gobert is a hospital physician (HCL) and a researcher at the Centre de Recherche en Neurosciences de Lyon (UCBL, CNRS, Inserm).

Anne-Sophie HAERINGER

Anne-Sophie Haeringer is a lecturer and researcher in sociology at the Centre Max Weber (Université Lyon 2, CNRS).

Julie HENRY

Julie Henry is a lecturer and researcher in philosophy at the Laboratoire Triangle (UMR 5206 CNRS, ENS Lyon, UL2, Sciences Po Lyon, UJM Saint-Etienne).

Raphaël MINJARD

Raphaël Minjard is a lecturer and researcher in psychology at the Centre de Recherche en Psychopathologie et Psychologie Clinique (Université Lyon 2).

Carole LARTIZIEN

Carole Lartizien is an image analysis researcher at the Centre de Recherche en Acquisition et Traitement de l’Image pour la Santé (CREATIS, CNRS, Inserm, UCBL, INSA, UJM).

Céline RACIN

Céline Racin is a lecturer and researcher in psychology at the Centre de Recherche en Psychopathologie et Psychologie Clinique (Université Lyon 2).

Fabien PERRIN

Fabien Perrin is a neuroscientist and faculty member at the Centre de Recherche en Neurosciences de Lyon (UCBL, CNRS, Inserm).

Partners

Speech-Language Pathologist, Post-ICU Rehabilitation Service

Hôpital neurologique de Lyon (HCL)

Mélaine DE QUELEN

Clinical psychologist and doctoral candidate

Centre de Recherche en Psychologie Clinique et Psychopathologie (Université Lumière Lyon 2)

Salomé CANN

Second-year Master’s student in Robotics and Artificial Intelligence Engineering

ENSTA

Basile MOLLARD

PhD student in neuroscience

Centre de Recherche en Neurosciences de Lyon (UCBL, CNRS, Inserm)

Bruno MICHELOT

Data Science Engineer

Centre de Recherche en Neurosciences de Lyon (UCBL)

Benjamin-Ousmane M’BENGUE

Psychologist

École de Psychologues Praticiens de l’Institut Catholique de Paris

Élodie BARAT

PU-PH

Service de Rééducation Post Réanimation de l’hôpital neurologique de Lyon (HCL)

Jacques LUAUTÉ

Research Engineer

Centre de Recherche en Neurosciences de Lyon (UCBL, CNRS, Inserm)

Alexandra CORNEYLLIE

PhD student in neuroscience

Centre de Recherche en Neurosciences de Lyon (UCBL, CNRS, Inserm)

Clémence BOBICHON

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